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Archives of Public Health

Springer Science and Business Media LLC

Preprints posted in the last 30 days, ranked by how well they match Archives of Public Health's content profile, based on 12 papers previously published here. The average preprint has a 0.02% match score for this journal, so anything above that is already an above-average fit.

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Food for frailty: Views of older adults on development and uptake of a foodbased frailty supplement

Valdes, A.; Hussain, B.; Timmons, S.

2026-04-07 nutrition 10.64898/2026.04.01.26348969 medRxiv
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Abstract Objective: Frailty is an important concern in old age. Inflammation can cause frailty. Anti-inflammatory food supplements can play a role in slowing down frailty processes and consequences. This study explored the views of people (aged 50-89 years) on the need to develop a frailty supplement, preferences for its form and how older people could be encouraged to use such a supplement. Design: We conducted semi-structured qualitative interviews and used a framework method to analyse the data. Participants: 30 participants from a city in the UK. Setting: These participants were recruited from social housing, care homes, foodbanks and the wider population. Participants were from diverse ethnic, gender and age backgrounds. Results: Participants identified a strong need for the development of a food-based supplement for frailty. They expressed excitement for the supplement and viewed it as something which they would be happy to integrate in their daily food routine. In terms of preferences, our participants wanted to have multiple options, however, a biscuit-based supplement was preferred by most. The participants preferences were mainly based on taste of the supplement, its effectiveness, convenience in use and affordability. Muslim participants in the sample said they would be happy to use this supplement if it was developed using Halal ingredients. In terms of creating awareness and encouraging people to use the proposed supplement, participants suggested a variety of marketing methods. These included: word of mouth, face to face sessions with older adults, social media, especially YouTube and advertising on TV. Conclusion: The participants were generally open to the idea of a food-based supplement and felt that it could easily fit with their existing food practices and lifestyles. Keywords: older adults, frailty, food supplement, co-creation, healthy ageing

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Development and Evaluation of iSupport-Malaysia: A Multimedia Web-Based Psychoeducational Intervention for Dementia Caregivers

Loh, K. J.; Lee, W. L.; Ng, A. L. O.; Chung, F. F. L.; Renganathan, E.

2026-04-21 geriatric medicine 10.64898/2026.04.14.26350743 medRxiv
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BackgroundCaring for people with dementia can impose a considerable psychological burden on caregivers, yet access to caregiver support in Malaysia remains limited. The World Health Organizations iSupport for Dementia program provides dementia education via textual, e-learning format. However, a culturally adapted Malaysian version has not been available. ObjectiveThis study aimed to develop and gather user feedback on a culturally adapted, multimedia version of iSupport tailored for Malaysia (iSupport-Malaysia). MethodsGuided by a four-phase cultural adaptation framework, the generic iSupport content was translated into Bahasa Malaysia, adapted to local customs, and transformed into multimedia lessons on an e-learning platform. A mixed-methods design was used to explore user perceptions and evaluate usability through four homogeneous focus group discussions and 15 individual usability test sessions with informal caregivers (FG: n=9; UT: n=9) and healthcare professionals (FG: n=11; UT: n=6). Focus groups examined aesthetics, ease of use, clarity, cultural relevance, comprehensiveness, and satisfaction. Usability testing involved Think Aloud tasks, post-test questionnaires, and brief interviews. Qualitative data was analysed thematically, and descriptive statistics summarised usability performance. ResultsiSupport-Malaysia demonstrated good usability (M=74.3{+/-}18.0), with most tasks completed without assistance. Strengths included interactive learning activities, peer discussion features, and flexible self-paced learning. Content was viewed as culturally appropriate, credible, and useful. Suggested improvements included enhancing visual aesthetics, shortening videos, refining quizzes, and increasing practical relevance. ConclusionUser insights indicate that iSupport-Malaysia is usable and culturally appropriate. These findings will inform refinement of the platform prior to the pilot feasibility study and provide recommendations for future multimedia-based caregiver interventions.

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The Beat Goes On: A Mixed-Methods Analysis in Developing Effective Police Leaver Transitions

Vaportzis, E.; Edwards, W.

2026-03-31 occupational and environmental health 10.64898/2026.03.26.26348236 medRxiv
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The end-of-career stage of the police lifecycle represents a profound shift in identity and psychological stability, yet it remains historically neglected in research. This mixed-methods study investigated perspectives of UK police leavers and those approaching retirement (N = 325) regarding desired improvements to organisational support. Content analysis identified four themes: Holistic support and long-term welfare, Institutional culture and professional worth, Navigating the structural transition, and Individual and systemic perspectives. Findings suggest that the psychological contract between the officer and the organisation is often breached at the exit point, shifting from a relational bond to a transactional disposal. Middle-ranking officers and early leavers report the highest levels of institutional abandonment. To address these gaps, this paper makes recommendations for developing effective transitions. By implementing post-service welfare, and adopting structured resettlement models, police organisations can fulfil their duty of care and mend the psychological contract for those who have served.

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Nutritional Knowledge And Associated Factors Among Pregnant Women In Ghana: A Cross-Sectional Study

Nkansah, M.; Salu, P. K.; Gyimah, L. A.

2026-04-17 nutrition 10.64898/2026.04.13.26350744 medRxiv
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BackgroundAdequate maternal nutritional knowledge is essential for healthy pregnancy outcomes, yet many pregnant women lack good nutritional knowledge. This study assessed nutritional knowledge and associated factors among pregnant women in the Krowor Municipality of Ghana. MethodsA facility-based cross-sectional study was conducted among pregnant women attending antenatal clinics in two public health facilities. Structured questionnaires were used to collect data on sociodemographic characteristics and nutritional knowledge. Data were analysed using descriptive statistics and chi-square tests at a 5% significance level. ResultsMost respondents demonstrated moderate nutritional knowledge (mean score =11.24 {+/-} 2.48), with 45% classified as having moderate knowledge. Income level (p = 0.00), education (p = 0.007), gestational age (p = 0.042), employment status (p = 0.007), and religion (p = 0.005) were significantly associated with nutritional knowledge. ConclusionThe study highlights notable gaps in nutritional knowledge among pregnant women in Krowor Municipality. Socioeconomic and obstetric factors strongly influenced nutritional knowledge. Strengthening antenatal nutrition counselling and improving socioeconomic support may help improve the nutritional knowledge of pregnant women.

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Evaluating the Impact of Socioeconomic Factors on Dietary Choices and Nutritional Status of Adults in Selected Urban and Rural Communities in Ekiti State

ADENIYI, B. M.; OGUNETIMOJU, A.; Olofinsanmabo, O. A.

2026-04-06 nutrition 10.64898/2026.03.31.26349759 medRxiv
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Introduction: Adults in Nigeria face a growing nutrition challenge: while some struggle with undernutrition, others are increasingly affected by overweight and obesity. This double burden of malnutrition reflects socioeconomic divides, where income, education, and household conditions shape food choices and health. This study examined how socioeconomic factors influence dietary diversity, nutritional knowledge, and nutritional status among adults in urban and rural communities of Ekiti State. Methods and Analysis: A descriptive cross-sectional survey was conducted among 350 adults selected via multistage sampling. Data were collected using structured questionnaires and anthropometric measurements. Dietary diversity was assessed using food group frequency, and nutritional status was determined by BMI. Associations were analyzed using chi-square tests (p < 0.05). Results: Significant urban-rural divides were identified: urban respondents were more educated (48.8% tertiary), while rural households were more dependent on farming (35.0%) and low-income (62.0% <70,000). Dietary patterns differed significantly: urban diets favored legumes (58.4%) and cereals (56.0%), while rural diets predominated in sugar/honey (90.0%) and roots/tubers (71.0%). Nutritional knowledge was higher in urban areas. Nutritional status revealed a dual burden: 20.4% of urban and 22.0% of rural respondents were underweight, while combined overweight/obesity affected 18.4% of urban and 25.0% of rural participants. Conclusion: Socioeconomic factors strongly dictate dietary choices and health in Ekiti State. Urban areas show greater diversity but rising obesity risks, while rural areas face persistent undernutrition. These findings highlight the need for tailored, state-specific interventions addressing both food insecurity and emerging diet-related chronic disease risks. Keywords: Socioeconomic factors, Dietary diversity, Nutritional knowledge, Double burden of malnutrition, Ekiti State, Nigeria.

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Measuring the impact of lived experience and caregiver engagement in research on the research conducted: development and pilot testing of an assessment tool

Hawke, L. D.; Hou, J.; Upham, K.; van Kesteren, M. R.; Munro, C.; Hauer, S.; Sendanyoye, C.; Halsall, T.; Quilty, L.; Hamilton, C.; Barbic, S. P.; Wang, W.

2026-04-03 health systems and quality improvement 10.64898/2026.04.01.26349956 medRxiv
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Background. People with lived/living experience of health conditions, as well as caregivers, are increasingly engaged in research. This study aimed to develop and pilot test a new tool measuring the impact of lived/living experience engagement on the research. The measure is called the Measure of Engagement Tool for Research and lived Experience (METRE). Method. We conducted a qualitative descriptive study among 28 people with lived/living experience and caregivers and 12 academic researchers to understand the impacts of engagement. Using the findings, we drafted the METRE. We pilot tested the METRE among 13 people with lived/living experience and caregivers and 10 academic researchers. Insights were used to refine the scale. Results. Qualitatively, participants identified multiple domains of impact of engagement on research, which guided scale development. Pilot testing of the draft METRE revealed it being straightforward to complete, providing a thorough evaluation of the impact of engagement. However, some areas of improvement were recommended. The draft items showed acceptable preliminary performance. Conclusions. An assessment tool is now available to assess the impact of lived/living experience engagement on the research. Additional research is required to evaluate its psychometric properties. Tools to evaluate the impact of engagement on research will help advance the science of engagement and support engaged research teams in their work.

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Implementation Outcomes of a Web-Based Platform for Reporting and Monitoring Continuous Quality Improvement (CQI) Activities: A Mixed-Methods Evaluation

Komba, P.; Simmonds, G.; Dunbar, E. L.; Bundy, K.; Irving-Mattocks, N.; McDowell, M.; Ghee, A. E.; Puttkammer, N.

2026-04-02 health systems and quality improvement 10.64898/2026.03.31.26349902 medRxiv
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Background Continuous Quality Improvement (CQI) is a core strategy for strengthening health systems, yet documentation and monitoring of CQI activities remain fragmented in many low- and middle-income country (LMIC) settings. In Jamaica, CQI has been institutionalized across priority programs, but it largely relies on paper-based tools and basic digital platforms that limit timely learning and oversight. To address these gaps, Jamaicas Ministry of Health and Wellness (MOHW), in collaboration with the Caribbean Training and Education Centre for Health (C-TECH), adapted a web-based CQI application using a participatory, human-centered design approach. Methods We conducted a formative, convergent mixed-methods evaluation across 24 healthcare facilities to assess early-stage implementation of the CQI app. Guided by the Implementation Outcomes Framework, we examined acceptability, adoption, appropriateness, and feasibility. Quantitative data were collected through a structured survey of healthcare workers (n=43), and qualitative data were gathered through five focus group discussions (n=33) and three key informant interviews with CQI leads. Survey data were summarized descriptively, and qualitative data were analyzed using rapid qualitative analysis. Findings were integrated using joint displays. Results Survey findings indicated moderate to high perceived acceptability and appropriateness of the CQI app, with 70% of participants reporting that it saved time and 67% noting that it aligned with facility goals. However, 19% reported never using it. Qualitative findings highlighted the apps value for improving CQI documentation, visualizing trends, and supporting supervisory oversight. Key barriers to sustained adoption included inconsistent internet connectivity, limited follow-up training, unclear team roles, and challenges integrating app use into routine workflows. Leadership engagement and alignment with existing CQI structures emerged as critical enablers. Conclusion This formative evaluation suggests that a digitally enabled CQI platform can strengthen documentation and oversight of quality improvement activities in resource-constrained health systems when embedded within supportive organizational and infrastructural contexts. Addressing foundational system readiness, including leadership engagement, capacity-building, and workflow integration, will be essential to realizing the CQI apps potential in Jamaica and similar LMIC settings.

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Effectiveness of a Socially Implemented Cognitive Decline Prevention Program: A Retrospective Observational Study

Kouzuki, M.; Fujita, K.

2026-04-11 geriatric medicine 10.64898/2026.04.08.26350304 medRxiv
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Background and ObjectivesMultifactorial interventions have been reported to be effective in improving cognitive function; however, their long-term effectiveness in community settings remains to be sufficiently examined. This study aimed to investigate the effects of a socially implemented multifactorial intervention program on dementia onset, long-term care insurance certification, and post-intervention cognitive and physical functions. MethodsThis retrospective observational study collected data from three municipalities. The study population comprised individuals suspected of having mild cognitive decline based on cognitive function screening tests conducted by March 31, 2024, and who had been invited to participate in a dementia prevention class, but had not applied for long-term care insurance at the time of the invitation. Participants were classified into class participation and non-participation groups for analysis. Most participants attended the class only once (intervention duration: 4 or 6 months). ResultsData from 104, 218, and 256 individuals were collected from the three municipalities, respectively. No significant association was found between class participation and suppression of dementia onset or long-term care insurance certification in any of the municipalities. Regarding pre-post comparisons among class participants, significant improvements in cognitive function and some physical functions were observed in all the three municipalities. ConclusionsThe multifactorial interventions implemented in community settings showed no effect on dementia onset or health outcomes. However, class participation was associated with improvements in cognitive function and some physical functions. These findings suggest that implementing programs based on evidence can achieve effects similar to those observed in studies conducted under ideal conditions.

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When Care Depends on the Caregiver: Lived Experiences of Latino Families Navigating Dementia Care Pathways

Mora Pinzon, M. C.; Pasqualini, R.; Navarro, V.; Rosales, M. d. C.; Franzese, O.; Perales-Puchalt, J.

2026-04-02 geriatric medicine 10.64898/2026.03.29.26349413 medRxiv
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Introduction. Latino families shoulder a disproportionate share of dementia care in the United States, yet encounter multilayered barriers that shape access, timeliness, and quality. This study explores the experiences of Latino care partners, focusing on how system-level, cultural, and linguistic factors shape dementia care. Methods. We conducted a qualitative study using semi-structured interviews with care partners of Latino individuals living with Alzheimer's disease and related dementias (ADRD). Interviews were conducted by phone or videoconference by a bilingual interviewer, and the interviews were recorded and transcribed verbatim. Data was analyzed using reflexive thematic analysis. Results. Twenty-three participants were recruited. Two meta-themes captured participants' experiences. (1) Mismatch Between the Healthcare System and the Lived Realities of Latino Families Affected by Dementia, which included three subthemes: a) Linguistic barriers that referred to the quality and dialect fit (over-literal jargon, unfamiliar regional vocabulary, poor adaptation to literacy); b) Cultural misfit, were dementia-care programs were not culturally or linguistically appropriate, or programs where cultural norms were disregarded; and c) Structural and systemic barriers, such as communication failures (e.g. voicemail loops, no responsiveness) and long waits/fragmented pathways that broke clinical momentum (e.g. months to a year for specialty appointment). The second theme was: The Central Role of the Latino Caregiver in Navigating Dementia Care, where, in the absence of pathway ownership, care partners served as navigators, interpreters, coordinators, and safety monitors, while also bearing the emotional and financial strain. Discussion: The narratives from care partners reveal specific mechanisms (e.g., caregiver hyper-advocacy and "maze-like" coordination failures) that, if addressed, can guide intervention design and policy aimed at redistributing coordination back to the system and improving outcomes for Latino families.

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Digital Health and Data Utilisation for Improved Primary Health Services Delivery: Multi-Site Perspectives from Quality Improvement Teams in Council Hospitals in Tanzania

Matimo, C. R.; Kacholi, G.; Mollel, H. A.

2026-04-17 health systems and quality improvement 10.64898/2026.04.10.26350674 medRxiv
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BackgroundDigital health plays an indispensable role in facilitating data analysis and use for enhancing healthcare delivery across health settings. However, there is scant information on the extent to which digital health influences the improvement of primary health services delivery through data use. This study examined the determinants that influence the use of digital health to improve health service delivery in council hospitals in Tanzania. MethodsA cross-sectional design was employed in six regions, involving 12 council hospitals. We used a self-administered questionnaire to collect data from 203 members of hospital quality improvement teams. Descriptive analysis was used to determine the frequency, proportion, and mean of responses, while bootstrapping analysis was conducted to test the statistically significant influence of digital health factors on data use for improving health service delivery. ResultsResults show moderate agreement on data compatibility for planning and decision-making, with 40.4% of respondents agreeing it supports ordering commodities, 43.8% for staff allocation, and 38.4% for planning. However, dissatisfaction was higher for user-friendliness (47.8%), reliability (up to 65.5%), and usefulness (up to 63.5%). Overall, 50.2% (M=2.74{+/-}0.87) disagreed that digital systems effectively support data use. Structural model analysis confirmed significant positive influence of usefulness ({beta}=0.199, p<0.001) and access to quality data ({beta}=0.729, p<0.001) on data use, which strongly impacted service delivery ({beta}=0.593, p<0.001), despite some factors showing no direct influence. ConclusionThe study finds that current digital health initiatives only modestly improve the user-friendliness, reliability, and usefulness of data systems, partly due to fragmented, non-interoperable platforms that burden data management. However, compatibility, usability, reliability, and usefulness of digital tools significantly enhance access to quality data and data-driven decisions. The study recommends strengthening and integrating existing systems and providing continuous digital health training to institutionalize data-informed decision-making.

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Trends and determinants of minimum dietary diversity among children aged 6-23 months from 2014 to 2022 in Bangladesh: An analysis of nationally representative data

Mahmud, I.; Mim, M. A.; Roba, K. T.; Huda, T. M.

2026-04-15 nutrition 10.64898/2026.04.13.26350794 medRxiv
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Introduction: Minimum dietary diversity (MDD) is a key indicator of complementary feeding among children aged 6-23 months. This study examines the prevalence, trends, and determinants of MDD in Bangladesh over the period 2014 - 2022. Design: Secondary analysis of the Bangladesh Demographic and Health Survey (BDHS) data between 2014 and 2022. The primary outcome was MDD defined as consumption of at least 5 of 8 food groups (MDD-8). We included 6,080 children aged 6-23 months to assess trends over time. The pooled datasets were used to identify factors associated with MDD-8. Multiple logistic regression was performed to assess the association between different factors and MDD-8, accounting for the complex survey design. Setting: Bangladesh Results: The proportion of children achieving MDD-8 increased from 26.4% in 2014 to 38.7% in 2017, but plateaued at 37.1% in 2022, with an average annual increase of 4.3% between 2014 and 2022. MDD-8 improved with child age. Higher odds of achieving MDD-8 were observed among children surveyed in later years, from wealthier households, with mothers who had >=4 ANC visits, received PNC, had higher education, were employed, and had media exposure. Older age and higher birth order were also associated with achieving adequate MDD. Children in Chattogram and Sylhet were less likely to meet MDD-8 compared to Dhaka. Conclusions: While dietary diversity improved between 2014 and 2017, progress stalled thereafter. Targeted, multisectoral strategies focusing on womens empowerment, health service utilisation, media engagement, and disadvantaged regions are needed to improve child dietary diversity in Bangladesh.

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Why Patients Choose Spiritual Healers, Alternative Medicine, and Unqualified Practitioners Before Formal Medical Care: An Exploratory Mixed Methods Study in Peri-Urban and Rural Faisalabad, Pakistan

Hamid, S.; Muneez, M.; Saleem, S.

2026-04-24 health systems and quality improvement 10.64898/2026.04.23.26351601 medRxiv
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ABSTRACT Background Before obtaining professional medical care, many people in peri-urban and rural Pakistan contact herbalists, spiritual healers, and unlicensed caregivers. This study examined the social, economic, and cultural factors influencing the use of informal care by analysing the health-seeking behaviours of individuals in the Faisalabad District. Methods An exploratory mixed-methods study was conducted in Makkuana and the surrounding villages of Faisalabad District, Punjab. The quantitative component involved a cross-sectional survey of 69 adults using a structured questionnaire adapted from the I-CAM-Q. The qualitative component comprised twelve in-depth interviews and two focus group discussions. Descriptive statistics and chi-square analysis were used for quantitative data. Thematic analysis, guided by the Health Belief Model and Andersen's Behavioural Model, was applied to qualitative data. Results The mean age of participants was 40.4 years; 62.3% were female, and 79.7% had monthly household incomes below PKR 60,000. Of the 69 participants, 68 (98.6%) sought care from an informal provider first, most commonly an unqualified practitioner (50.7%), herbal practitioner (29.0%), or homeopath (17.4%). Trust was the leading reason for provider choice (43.5%), followed by proximity (24.6%) and low cost (15.9%). Complications were reported by 21.7% of participants, and 39.1% later required formal care for the same illness. Eight qualitative themes emerged: structural and economic barriers to formal care; proximity and convenience as determinants of informal care; trust, familiarity, and social networks; cultural and religious normalisation of traditional practices; poor doctor-patient communication in formal settings; perceived safety and naturalness of alternative remedies; awareness deficits about provider qualifications; and treatment-related harm and delayed escalation to formal care. Conclusion Informal health care seeking is nearly universal in this community, driven by intersecting economic, structural, cultural, and interpersonal factors. Enhancing primary care affordability, accessibility, and the quality of provider-patient communication together with culturally sensitive health literacy programs, is essential to redirect care seeking toward qualified providers.

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Evaluating a Multitask AI Model versus Humans for Portion Size Estimation

Nurmanova, B.; Omarova, Z.; Sanatbyek, A.; Varol, H. A.; Chan, M.-Y.

2026-04-18 nutrition 10.64898/2026.04.16.26351036 medRxiv
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Background: Accurate dietary assessment is essential for precision nutrition and effective nutrition surveillance. However, portion size estimation remains a persistent challenge, particularly in culturally diverse regions such as Central Asia. Traditional self-reporting tools often yield inconsistent results due to communal eating practices and unfamiliarity with standard measures. Objective: To address these limitations, this study aimed to compare three methods: unassisted human judgment, visual food atlas assistance, and an artificial intelligence (AI) model, using Central Asian food items. Methods: In this cross-sectional study, 128 participants from Astana, Kazakhstan, visually estimated portion sizes of 51 foods and 8 beverages from standardized photographs. Participants were randomized into two groups: one using unassisted visual estimation and the other aided by a regionally tailored digital food atlas. Additionally, an AI model trained on Central Asian food images was evaluated. Actual food weights served as the reference standard. Accuracy was assessed using Mean Absolute Error (MAE) and Mean Absolute Percentage Error (MAPE) across food types and portion sizes. Results: The atlas-assisted group demonstrated the highest accuracy, with the lowest MAE (80.81g) and MAPE (44.76%) across all portions. The AI model showed promising results for average portions (MAE: 79.07g, MAPE: 67.91%) but underperformed on small portions, particularly for meat-based items. Unassisted estimates were the least accurate (MAE: 133.86g, MAPE: 79.40%). Across food categories, visual aids consistently improved accuracy, while AI demonstrated variability by texture and portion size. Conclusions: Culturally adapted visual atlases significantly enhance portion size estimation accuracy in non-Western, communal-eating contexts. While AI models hold promise for dietary assessments, particularly with standard portions and beverages, further refinement is needed for complex food items and small portion types. These findings support the integration of visual and AI-based tools into region-specific dietary monitoring strategies.

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Effect of a theory-driven health education intervention on personal protective equipment use among commercial motorcycle riders in Cameroon: A quasi-experimental study

Ukah, C. E.; Tendongfor, N.; Hubbard, A.; Tanue, E. A.; Oke, R.; Bassah, N.; Yunika, L. K.; Ngu, C. N.; Christie, S. A.; Nsagha, D. S.; Chichom-Mefire, A.; Juillard, C.

2026-04-12 public and global health 10.64898/2026.04.08.26350441 medRxiv
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BackgroundCommercial motorcycle riders are among the most vulnerable road users in low- and middle-income countries and contribute substantially to the burden of road traffic injuries. The use of personal protective equipment (PPE), including helmets and protective clothing, reduces injury severity; however, uptake remains suboptimal. This study evaluated the effectiveness of a theory-driven health education intervention in improving knowledge, attitudes, and use of PPE among commercial motorcycle riders in Cameroon. MethodsA quasi-experimental, non-randomized controlled before-and-after study was conducted in Limbe (intervention) and Tiko (control) Health Districts between August 4, 2024, and April 6, 2025. Participants were recruited from a cohort of commercial motorcycle riders and followed over an eight-month intervention period. The intervention, guided by the Health Belief Model and developed using the Intervention Mapping framework, combined face-to-face sensitization sessions with mobile phone-based educational messaging adapted to participants literacy levels and communication preferences. Data were collected at baseline and endline using structured questionnaires and direct observation checklists. Intervention effects were estimated using difference-in-differences analysis with generalized estimating equations, adjusting for socio-demographic factors. ResultsA total of 313 riders were enrolled at baseline (183 intervention, 130 control), with 249 retained at endline (149 intervention, 100 control). The intervention was associated with significant improvements in PPE knowledge ({beta} = 2.91; 95% CI: 2.14-3.68; p < 0.001) and attitudes ({beta} = 5.76; 95% CI: 4.32-7.21; p < 0.001) compared with the control group. No statistically significant effect was observed for PPE practice scores ({beta} = 0.21; 95% CI: -0.09-0.52; p = 0.171). Among individual PPE items, helmet use increased significantly in the intervention group relative to the control group (AOR = 2.38; 95% CI: 1.19-9.45; p = 0.036), while no significant effects were observed for gloves, trousers, eyeglasses, or closed-toe shoes. ConclusionThe theory-driven health education intervention significantly improved knowledge and attitudes toward PPE and increased helmet use among commercial motorcycle riders but did not lead to broader improvements in the uptake of other protective equipment. These findings highlight the need for complementary structural and policy interventions to address persistent barriers to PPE use in similar low-resource settings. Trial registrationClinicalTrials.gov Identifier: NCT07087444 (registered July 28, 2025, retrospectively)

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A Protocol for Identifying Priorities for Women+ Health in the Maritime Provinces using a Priority Setting Partnership Approach

Dol, J.; Pritchett, C.; Larocque, L.; Bentley, J.; Brooks, M.; Elliott Rose, A.; Rosen, N.; Davies, E.; Yeluri, M.; Gosse, M.

2026-04-03 health systems and quality improvement 10.64898/2026.04.02.26350048 medRxiv
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Background/Objectives: Women+ (e.g., women and individuals assigned female at birth) experience disproportionate health risks and persistent gaps in access to care, despite regionally coordinated health systems. Women+ health research remains significantly underfunded and understudied, contributing to inequities in diagnosis, treatment, and outcomes. This study aims to collaboratively identify and prioritize the most pressing unanswered research questions related to women+ health in the Maritime provinces of Canada. Methods: This study will use a modified Priority Setting Partnership (PSP) methodology based on the James Lind Alliance framework. A mixed-methods participatory approach will be used, including bilingual online surveys (French, English) and a one-day consensus workshop. Participants will include women+, healthcare professionals, researchers, policymakers, and the public residing in the Maritime provinces (Nova Scotia, New Brunswick, and Prince Edward Island). An initial survey will collect research uncertainties through open-ended questions. A second interim survey will rank verified uncertainties, followed by a facilitated workshop to achieve consensus on the Top 10 research priorities. Qualitative data will be analyzed using content analysis, and descriptive statistics will summarize participant demographics. Anticipated Results: This project is expected to generate a collaboratively developed, evidence-informed Top 10 list of research priorities for women+ health in the Maritimes. The process will also identify thematic gaps in existing research and assess feasibility considerations to inform future study design and implementation. Conclusions: By centering women+ voices and engaging diverse interest holders, this study will establish a shared regional research agenda to guide future research, funding, and policy initiatives for women+ health research.

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Infodemic Management Challenges and Training Needs Among Frontline Health Educators in Lagos State Nigeria

Erim, A.; Lansana, P.; Badmus, O.; Olanrewaju, M. F.

2026-04-11 health systems and quality improvement 10.64898/2026.04.09.26350557 medRxiv
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Misinformation circulating through digital platforms and community networks increasingly challenges public health communication, particularly in low- and middle-income countries. Frontline health educators play a critical role in addressing misinformation and promoting accurate health information within primary health care systems; however, empirical evidence on their preparedness to manage infodemics remains limited. This study assessed the training needs and response capacity of primary health care health educators in Lagos State, Nigeria. A convergent mixed-methods design was employed across three districts. Quantitative data were collected from 95 health educators using the 30-item Health Educators Infodemic Management Training Needs Assessment Questionnaire (HEIM-TNAQ). Qualitative data were obtained through six focus group discussions involving 56 educators and 25 key informant interviews with supervisors and programme managers. Quantitative data were analysed using descriptive statistics and t-tests, while qualitative data were analysed thematically. Participants demonstrated relatively strong knowledge of health misinformation (mean = 71.5), but only moderate decision-response skills (48.6) and low confidence in addressing misinformation (42.5). Integration of misinformation response into routine practice was also limited (46.3), and no significant differences were observed between respondents with or without prior training. Qualitative findings revealed frequent exposure to vaccine rumours, spiritual explanations for illness, and misinformation circulating through social media and community networks. Strengthening infodemic management within primary health care requires practical training, behavioural communication skills, and institutional mechanisms for systematic rumour monitoring and response.

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Determinants of Skilled Birth Attendance in Nigeria: A Population-Based Analysis of the 2018 Demographic and Health Survey

Unegbu, U. L.

2026-04-23 epidemiology 10.64898/2026.04.23.26350432 medRxiv
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Background: Nigeria bears one of the highest maternal mortality burdens globally, with skilled birth attendance (SBA) remaining critically low in many regions. Understanding the independent determinants of SBA is essential for designing targeted interventions. Methods: This cross sectional study analyzed 21,465 births from the 2018 Nigeria Demographic and Health Survey (NDHS), a nationally representative household survey using stratified two stage cluster sampling. SBA was defined as delivery attended by a doctor, nurse, midwife, or auxiliary midwife. Multivariable logistic regression was used to estimate adjusted odds ratios (aOR) with 95% confidence intervals for the associations between SBA and maternal education, household wealth, place of residence, geopolitical region, maternal age, parity, and antenatal care (ANC) utilization, after accounting for confounding. Results: The overall prevalence of SBA was 44.9%. In the fully adjusted model, higher education (aOR = 7.01, 95% CI: 5.68-8.67), richest wealth quintile (aOR = 6.27, 95% CI: 5.27-7.46), and attending [&ge;]4 ANC visits (aOR = 3.80, 95% CI: 3.51-4.11) were the strongest independent predictors of SBA. Regional inequalities were pronounced, with SBA prevalence ranging from 17.7% in the North West to 85.6% in the South West. Crude effect estimates for education and wealth were substantially attenuated after adjustment, indicating large confounding by correlated socioeconomic factors. Conclusions: Maternal education, household wealth, ANC utilization, and geopolitical region are independent determinants of SBA in Nigeria. Scaling up ANC programs represents the most immediately actionable intervention, while long term gains require investment in girls' education and wealth equity. Targeted strategies for the northern regions are urgently needed. Keywords: skilled birth attendance, maternal mortality, Nigeria, DHS, antenatal care, logistic regression, health equity

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The Hospital Murals Evaluation: A mixed-methods evaluation of the impact of murals on patients, healthcare workers, and visitors

Sajnani, N.; Foster, M. W.; Oshodi, Y.; Sodimu, K. A.; Kolnik, M.; Pokorn, M.; Simpson, N.; Shaw, T.; Willmoth, S.; Marino, M.; Trinder, L.; Akisanya, E.; Onyekachi, E.; Bahr, E.; Blanchette, V.; Assistant, R.; Bolt, E.; Gong, Q.; Fenning, H. M.; Komolafe, D. O.; Murden, R.; Omuku, N.; Rowe, C.; Sanhueza, C.; Steer, T.; Trupp, M. D.; White, N.; Wu, Y.

2026-04-13 health systems and quality improvement 10.64898/2026.04.09.26350479 medRxiv
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ObjectiveThis study investigated how hospital murals influence the experiences of patients, healthcare staff, and visitors across four sites. BackgroundEvidence shows that visual art in healthcare settings can improve well-being but few studies focus specifically on murals or compare their effects across cultural contexts. The Hospital Murals Evaluation project addresses this gap through an investigation of murals in hospitals in Nigeria, Slovenia, the United Kingdom, and the United States. MethodsUsing a mixed methods cross-sectional design, the study integrated surveys, interviews, and participatory photography. A total of 525 unique responses were collected from 229 patients (131 adult, 98 pediatric), 245 staff, 49 visitors, and 2 undisclosed. ResultsInterviews across all three participant groups (n=115) revealed themes of positive affects, perception of care, as well as stress or indifference. Surveys (n=327) showed moderate positive correlations between mural viewing and positive emotions among patients, and between mural exposure and well-being, positive emotions, social connection, and workplace belonging among staff in the UK and USA, with null findings for staff in Nigeria and Slovenia. Participatory photography (n=83) illustrated how murals conveyed comfort, though abstract or poorly placed murals sometimes evoked discomfort. Meta-inferences across the methods indicate that viewing murals were associated with positive emotions for patients and did not induce negative emotions for staff or visitors. ConclusionMurals act as health-promoting infrastructure that can enhance well-being, foster positive experiences, and signal intentions of care. The findings highlight the need for culturally attuned designs to create healthcare environments that nurture well-being.

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On the road to early detection: A survey study of barriers and facilitators to community participation in a mobile lung cancer screening program

Cottrell-Daniels, C.; Sadig, N.; Haddan, S.; Roman, S.; Simmons, V. N.; Schabath, M. B.

2026-04-17 epidemiology 10.64898/2026.04.15.26350954 medRxiv
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Background While a mobile lung cancer screening (mLCS) program can mitigate barriers to access, this study conducted a survey study to assess barriers and facilitators to mLCS which could inform the implementation of new mLCS programs or inform modifications to existing programs. Methods Patient eligibility included current age of 50 to 80 and had undergone any cancer screening at Moffitt Cancer Center (MCC) between January 1, 2023 and December 1, 2024. A web-based survey was administered from May 2025 to June 2025 which collected data on health behaviors, barriers, facilitators, screening preferences, and demographics. Descriptive statistics were used to quantify survey responses. Results Among participants who completed the survey, 73.4% reported no concerns about getting screened in a mobile screening unit, 67.9% reported concerned about the cost or if insurance covered mobile lung cancer screening, and 82.4% reported they would be screened if a voucher or insurance would pay for it. For preferences, 54.1% reported no preference for the time of year for a mobile screening event, 59.6% reported they will be willing to wait up to 30 minutes to get screened, and 44% would travel more than 20 minutes to get screened. There were no statistically significant differences in barriers and facilitators when the analyses were stratified by LCS eligibility. Conclusions We found acceptability of mobile lung cancer screening and preferences that are actionable including daytime weekday events, indoor waiting, short waits, proximity to home, clear cost coverage, and streamlined clinician recommendation.

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Thoracostomy Tube Infections: Prevalence and Associated Clinical Characteristics at a Tertiary Hospital in Northern Tanzania

Rwomurushaka, E. S.; Damas, L.; Niccodem, E.; Mwakyembe, T. E.; Msuya, D.; Chilonga, K.; Sango, M.

2026-04-17 surgery 10.64898/2026.04.15.26350981 medRxiv
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Background: Chest tube infection is one of the complications of the tube thoracostomy. Infectious complications may develop in 2% to 25% of patients who undergo thoracotomy tube placement. The use of prophylactic antibiotics to prevent infections associated with thoracostomy tubes remains a subject of debate. Current practices in managing infections related to tube thoracostomy are hindered by the lack of comprehensive and localised data on the microbial profile and their resistance patterns. Objective: To determine the prevalence of thoracostomy tube infections and associated clinical characteristics among patients treated with a thoracostomy tube at KCMC Zonal Referral Hospital. Methodology: Prospective cohort study done at KCMC Zonal Referral Hospital. Include all patients undergoing thoracostomy tube insertion from September 2024 to April 2025. Results: A total of 84 patients underwent tube thoracostomy during the study time. Of these 22 (26.2%) developed SSI. Out of the 22 samples collected, 17 (77.3%) had positive culture results. The most commonly identified pathogens were Pseudomonas aeruginosa (41.2%) and Staphylococcus aureus (29.4%). The highest overall susceptibility was observed with amikacin, effective against 10 (58.8%) of the tested organisms. The most common resistance was observed against ceftazidime (56.3%) and piperacillin-tazobactam (50.0%). Prolonged chest tube duration (>7 days) was the strongest independent predictor of tube thoracostomy infection. Conclusion: This study revealed a high prevalence of tube thoracostomy infection. Prolonged tube duration and admission to a non-surgical ward care emerge as key risk factors for SSI. These findings underscore the importance of limiting chest tube duration when clinically feasible and ensuring optimal postoperative care environments to minimise the risk of infection.